In 1858, four members of the Daughters of Charity of St. Vincent de Paul opened a small hospital in the Aguilar Adobe on Upper Main Street. This became the first hospital in Los Angeles (also see First Orphanage in Los Angeles). The sisters had arrived in California from Maryland a few years earlier at the request of the Bishop of Los Angeles and Monterey. By 1884, they had opened a larger hospital on Sunset and Beaudry. This eventually became St. Vincent's Hospital and is now St. Vincent's Medical Center.