In 1856, after arriving in California from Maryland at the request of the Bishop of Los Angeles and Monterey, four members of the Daughters of Charity of St. Vincent de Paul opened a small school and orphanage in Los Angeles (also see First Orphanage in Los Angeles). Shortly thereafter, they also began caring for the sick. This became a hospital in an abode owned by then-Los Angeles Mayor Don Cristóbal Aguilar on Upper Main Street and the first hospital in Los Angeles. In 1860, they relocated to Naud Street. By 1884, they had opened a larger hospital, the Los Angeles Infirmary, on Sunset and Beaudry. In 1918, it was renamed St. Vincent's Hospital and, in 1974, St. Vincent's Medical Center.